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Therapy with any combination of lisinopril and hydrochlorothiazide may be associated with either or both dose-independent or dose-dependent side effects, but addition of lisinopril in clinical trials blunted the hypokalemia normally seen with diuretics.

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Information about Hydrochlorothiazide.

Do not let anyone else take your medicineAsk your pharmacist any questions you have about refilling your prescription.

Take this medication by mouth as directed by your doctorusually once daily in the morning with or without foodIf you take this drug too close to bedtimeyou may need to wake up to urinateIt is best to take this medication at least 4 hours before your bedtime.

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Use this medication regularly to get the most benefit from itTo help you remembertake it at the same time each dayKeep taking this medication even if you feel wellMost people with high blood pressure do not feel sick.

Thiazides do not affect normal blood pressureOnset of action occurs within 2 hours of dosingpeak effect is observed at about 4 hoursand activity persists for up to 24 hours.

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